Postdoc in pancreatic cancer metabolism

Profilbillede
dato

BEMÆRK: Ansøgningsfristen er overskredet

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of pancreatic cancer metabolism as per 1 March 2024 or as soon as possible thereafter. The position is a fixed-term full-time position for 2 years.

The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research. You can read more about the department here and about the faculty here.
 

About the research project

Our lab is focused on understanding the rewired metabolism of pancreatic cancer (PDAC) cells and how it contributes to tumor growth and drug resistance. Using in vitro and in vivo PDAC models, we recently described metabolic vulnerabilities in pyrimidine synthesis (PMID: 30470748) and ferritinophagy, a process that mediates iron release in the lysosome to support mitochondrial respiration (PMID: 35771492). In addition to the rewired metabolism in cancer cells, metabolic cross-talk with elements of the tumor microenvironment (e.g. immune populations), can also support PDAC growth and drug response. Using cell culture-based studies, proteomics, and mouse models of PDAC, this project will explore how inhibition of metabolic processes can interfere with cancer cell growth while modulating anti-tumoral immune responses that could facilitate combinatorial approaches with immune modulators.

Your job responsibilities

As Postdoc in pancreatic cancer metabolism your position is primarily research-based but may also involve teaching assignments. You will contribute to the development of the department through research and teaching of high international quality. In your daily work, you will work closely with colleagues on your project, where you will receive supervision and guidance.

Your main tasks will consist of:

  • Independent research of high international quality, including publication.
  • Cell culture, including cancer and immune cell culture/co-culture techniques.
  • Analysis of gene and protein expression in cell and tissue lysates.
  • Animal experimentation, including tumor cell injection, dosing and tissue harvests.
  • Immunohistochemistry.
  • Flow citometry.
  • Assisting in proteomics sample preparation and data analysis.
  • Contributing to the preparation of manuscripts, and ideally fellowship applications.
  • Help in the supervision of a junior scientist in the lab.
  • Present our work at meetings, conferences, or workshops.
You will report to Assistant Professor Naiara Santana Codina

Your competences

You have academic qualifications at PhD level, for example within the following areas molecular biology, biochemistry, cancer biology. Experience with flow citometry, mouse models of cancer and data analysis is desirable.
As a person you are highly motivated, inclusive, independent yet willing to collaborate with other team members and eager to develop a novel research program. We expect you to be fluent in oral and written English and possess good communication and interpersonal skills.
In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

Questions about the position

If you have any questions about the position, please contact Dr. Naiara Santana Codina by email: nsc@biomed.au.dk, tel.: +4531157015. E-mail contact is preferred.

Your place of work will be the Department of Biomedicine, Anatomy Building, Wilhelm Meyers Allé 3, 8000 Aarhus C, Denmark.

We expect to conduct interviews from August onwards.


Terms of employment




Application


Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant - postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)
We refer to the faculty’s Guidelines for applicants.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.


International applicant?


Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.


Aarhus University

Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at www.international.au.dk/

INFORMATIONER OM STILLINGEN:

- Arbejdspladsen ligger i:

Aarhus Kommune

-Virksomheden tilbyder:

-Arbejdsgiver:

Aarhus Universitet, Wilhelm Meyers Allé 3, 8000 Aarhus C

-Ansøgning:

Ansøgningsfrist: 19-12-2023; - ansøgningsfristen er overskredet

Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5945647

Denne artikel er skrevet af Emilie Bjergegaard og data er automatisk hentet fra eksterne kilder, herunder JobNet.
Kilde: JobNet