Postdoc in hematopoietic stem cell biology and CRISPR/Cas9 transcriptional engineering

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dato

BEMÆRK: Ansøgningsfristen er overskredet

The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of hematopoietic stem cell biology and CRISPR/Cas9 transcriptional engineering as per 19. October 2023 or as soon as possible thereafter. The position is an 18-month fixed-term full-time position.

The department of Biomedicine prioritises diversity and a good work environment, as this is a prerequisite for groundbreaking research. In a diverse and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in professional scientific basic research. You can read more about the department here and about the faculty here.

About the research group

The research group is led by Associate Professor Rasmus O. Bak. The group specializes in genetic engineering using various CRISPR/Cas platforms, and we mainly focus on applying these for gene therapy and the development of novel cell therapies. The research group is supported by several major grants and is based in the new Skou Building in the heart of the Aarhus University campus. For more information on the research group, please visit our homepage.

About the research project

The research project will leverage the unique power of repurposed CRISPR/Cas systems for precise transcriptional manipulation of human hematopoietic stem and progenitor cells (HSPCs). These state-of-the-art CRISPRa and CRISPRi tools will be further developed in this project and used to study and manipulate the biology and therapeutic capacity of HSPCs in regenerative medicine and hematological disorders.

Your job responsibilities

The Postdoc position is primarily research-based but will also involve teaching assignments. You will contribute to the development of the department through research of high international quality.

Your main tasks will consist of:

  • Plasmid cloning, cell culturing, transfection, CRISPR/Cas genetic engineering, and lentiviral vector production.
  • Genetic, phenotypic, and functional characterization of hematopoietic stem cell properties in vitro and in vivo.
  • Analysis, interpretation, and presentation of research data including publication in peer-reviewed journals.

You will be under daily supervision and guidance by group leader Rasmus O. Bak, and you will formally report to the Head of Department Thomas G. Jensen.

Your competences

Applicants must have academic qualifications at PhD level in medicine, molecular medicine/biology, biotechnology, or similar. Experience in one or more of the following techniques is highly desirable: hematopoietic stem cell culturing, CRISPRa/i-based transcriptional manipulation, CRISPR/Cas gene editing, flow cytometry, mouse transplantation, and production of viral vectors. The applicant should be highly motivated, scientifically curious, and a self-starter. Excellent communication and inter-personal skills are a prerequisite. We expect you to be fluent in oral and written English.

In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.

Shortlisting will be used.

Questions about the position

If you have any questions about the position, please contact Rasmus O. Bak; e-mail: bak@biomed.au.dk.

Your place of work will be the Department of Biomedicine, Skou Building, Høegh-Guldbergsgade 10, bldg. 1115, DK-8000 Aarhus C., Denmark.


Terms of employment



Application

Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • Template for applicant - postdoc
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
  • Research plan can be uploaded (optional)
  • Coauthor statement(s) can be uploaded (optional)
  • References/recommendations can be uploaded separately in the e-recruitment system (optional)
We refer to the faculty’s Guidelines for applicants.

The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.

Letter of reference

If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.

International applicant?

Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.

The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.


Aarhus University

Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at www.international.au.dk/

INFORMATIONER OM STILLINGEN:

- Arbejdspladsen ligger i:

Aarhus Kommune

-Virksomheden tilbyder:

-Arbejdsgiver:

Aarhus Universitet, Høegh-Guldbergs Gade 10, 8000 Aarhus C

-Ansøgning:

Ansøgningsfrist: 28-07-2023; - ansøgningsfristen er overskredet

Ved skriftlig henvendelse: https://AU.emply.net/recruitment/vacancyApply.aspx?publishingId=462afb84-71e6-497c-811d-a27af662ad6a

Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5878187

Denne artikel er skrevet af Emilie Bjergegaard og data er automatisk hentet fra eksterne kilder, herunder JobNet.
Kilde: JobNet